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| Product Name | BAY 41-2272 |
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| Description | Activator of soluble guanylyl cyclase (sGC); acts at a nitric oxide (NO)-independent regulatory site in the sGC α1 subunit. Inhibits platelet aggregation (IC50 = 36 nM) and phenylephrine-induced contractions of rabbit aorta (IC50 = 0.30 μM). Also reduces vascular smooth muscle growth through cAMP- and cGMP-dependent PKA and PKG pathways. Purity 98%. MW (observed): 360.39 |
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| Size | 50 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | 5-Cyclopropyl-2-[1-[(2-fluorophenyl)methyl]-1H-pyrazolo[3,4-b]pyridin-3-yl]-4-pyrimidinamine |
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| Gene, Accession, CAS # | CAS: 256376-24-6 |
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| Catalog # | 4430/50 |
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| Order / More Info | BAY 41-2272 from TOCRIS BIOSCIENCE
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| Product Specific References | n/a |
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