| 产品详情 |
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| Product Name | BAY 60-6583 |
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| Description | Potent adenosine A2B receptor agonist (EC50 = 2.83 nM for murine A2B receptor). Displays selectivity for A2B over A1, A2A and A3 receptors. Decreases fMLP-induced superoxide production in neutrophils at low concentrations (1-10 nM). Cardioprotective; attenuates infarct size in a mouse model of myocardial ischemia. Exhibits ERK1/2-biased agonism. Purity 98%. MW (observed): 379.44 |
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| Size | 50 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | 2-[[6-Amino-3,5-dicyano-4-[4-(cyclopropylmethoxy)phenyl]-2-pyridinyl]thio]-acetamide |
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| Gene, Accession, CAS # | CAS: 910487-58-0 |
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| Catalog # | 4472/50 |
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| Order / More Info | BAY 60-6583 from TOCRIS BIOSCIENCE
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| Product Specific References | PubMed: 24403862, 25850656, 26370839, 27760305, 27974241, 28054654, 28169986 |
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