| 产品详情 |
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| Antigenic Specificity | CD45RC |
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| Clone | C455.1F |
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| Host Species | Rat |
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| Reactive Species | mouse |
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| Isotype | IgG2a, kappa |
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| Format | fluorescein (FITC) conjugate |
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| Size | 500 µg |
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| Concentration | n/a |
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| Applications | Flow Cytometry: 0.1-0.25 µg / 1x10^6 cells |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | CD45RC Monoclonal Antibody (C455.1F), FITC. CD45RC (PTPRC) is a protein tyrosine-protein phosphatase required for T-cell activation through the antigen receptor. It acts as a positive regulator of T-cell coactivation upon binding to DPP4. The first PTPase domain has enzymatic activity, the second affects the substrate specificity of the first. Upon T-cell activation, CD45RC recruits and dephosphorylates SKAP1 and FYN. Mutations of the gene can result in severe combined immunodeficiency and multiple sclerosis. |
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| Immunogen | n/a |
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| Other Names | B220, CD45R, Cd45, Ly-5, Lyt-4, T200, cluster designation 45RC |
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| Gene, Accession # | Entrez: 19264; Uniprot: P06800 |
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| Catalog # | RMCD45RC01 |
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| Price | |
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| Order / More Info | CD45RC Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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