| 产品详情 |
| Edit |   |
|---|
| Antigenic Specificity | CD45RC |
|---|
| Clone | OX-22 |
|---|
| Host Species | Mouse |
|---|
| Reactive Species | rat |
|---|
| Isotype | IgG1 |
|---|
| Format | biotin conjugate |
|---|
| Size | 100 ug |
|---|
| Concentration | n/a |
|---|
| Applications | Flow Cytometry: 0.1 µg/1x10^6 cells, Immunohistochemistry (Frozen): Assay Dependent |
|---|
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
|---|
| Description | CD45RC Monoclonal Antibody (OX-22), Biotin. CD45RC (PTPRC) is a protein tyrosine-protein phosphatase required for T-cell activation through the antigen receptor. It acts as a positive regulator of T-cell coactivation upon binding to DPP4. The first PTPase domain has enzymatic activity, the second affects the substrate specificity of the first. Upon T-cell activation, CD45RC recruits and dephosphorylates SKAP1 and FYN. Mutations of the gene can result in severe combined immunodeficiency and multiple sclerosis. |
|---|
| Immunogen | n/a |
|---|
| Other Names | B220, CD45R, Cd45, Ly-5, Lyt-4, T200, cluster designation 45RC |
|---|
| Gene, Accession # | Entrez: 24699; Uniprot: P04157 |
|---|
| Catalog # | MA5-17458 |
|---|
| Price | |
|---|
| Order / More Info | CD45RC Antibody from INVITROGEN ANTIBODIES |
|---|
| Product Specific References | n/a |
|---|
| 产品资料 |
|
|