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| Antigenic Specificity | Phospho-TGFBR2 (Ser225, Ser250) |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human, mouse, rat |
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| Isotype | n/a |
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| Format | purified |
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| Size | 100 µl |
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| Concentration | n/a |
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| Applications | Immunohistochemistry (Paraffin): 1:50-1:100 |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Phospho-TGFBR2 (Ser225, Ser250) Polyclonal Antibody. This gene encodes a member of the Ser/Thr protein kinase family and the TGFB receptor subfamily. The encoded protein is a transmembrane protein that has a protein kinase domain, forms a heterodimeric complex with another receptor protein, and binds TGF-beta. This receptor/ligand complex phosphorylates proteins, which then enter the nucleus and regulate the transcription of a subset of genes related to cell proliferation. Mutations in this gene have been associated with Marfan Syndrome, Loeys-Deitz Aortic Aneurysm Syndrome, and the development of various types of tumors. Alternatively spliced transcript variants encoding different isoforms have been characterized. |
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| Immunogen | n/a |
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| Other Names | TGFBR2, TGF-beta receptor type-2, TGF-beta type II receptor, Transforming growth factor-beta receptor type II |
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| Gene, Accession # | Entrez: 21813, 7048, 81810; Uniprot: P37173, P38438, Q62312 |
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| Catalog # | PA5-37755 |
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| Price | |
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| Order / More Info | Phospho-TGFBR2 (Ser225, Ser250) Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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