| 产品详情 |
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| Antigenic Specificity | GRB2 |
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| Clone | 2GB04 (C1.4) |
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| Host Species | Mouse |
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| Reactive Species | bovine, human, mouse, rat, Xenopus laevis |
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| Isotype | IgG1, kappa |
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| Format | purified |
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| Size | 500 µl |
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| Concentration | n/a |
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| Applications | Immunofluorescence: Assay Dependent, Immunohistochemistry (Paraffin): Assay-Dependent |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | GRB2 Monoclonal Antibody (2GB04 (C1.4)). GRB 2 protein contains one SH2 domain flanked on both sides by an SH3 domain. In response to EGF, GRB 2 binds, through its SH3 domains, to the guanine nucleotide exchange factor, Sos. The GRB 2 - Sos complex then binds the EGF receptor. These interactions play a critical role in the activation of the p21 ras signalling pathway. |
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| Immunogen | n/a |
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| Other Names | ASH, EGFRBP-GRB2, Grb3-3, MST084, MSTP084, NCKAP2, HT027, SH2/SH3 adapter GRB2, abundant SRC homology, epidermal growth factor receptor-binding protein GRB2, growth factor receptor-bound protein 3, protein Ash |
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| Gene, Accession # | Entrez: 14784, 2885, 535298, 81504; Uniprot: P62993, P62994, Q60631 |
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| Catalog # | AHO0522 |
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| Price | |
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| Order / More Info | GRB2 Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | PubMed: 21508326 |
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| 产品资料 |
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