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| Antigenic Specificity | Phospho-Transferrin Receptor (Ser24) |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human |
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| Isotype | n/a |
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| Format | purified |
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| Size | 100 µl |
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| Concentration | n/a |
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| Applications | Western Blot: 1:500-1:2000 |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Phospho-Transferrin Receptor (Ser24) Polyclonal Antibody. Cellular uptake of iron occurs via receptor-mediated endocytosis of ligand-occupied transferrin receptor into specialized endosomes. Endosomal acidification leads to iron release. The apotransferrin-receptor complex is then recycled to the cell surface with a return to neutral pH and the concomitant loss of affinity of apotransferrin for its receptor. Transferrin receptor is necessary for development of erythrocytes and the nervous system (By similarity). A second ligand, the heditary hemochromatosis protein HFE, competes for binding with transferrin for an overlapping C-terminal binding site. |
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| Immunogen | n/a |
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| Other Names | TFRC; Transferrin receptor protein 1; TR; TfR; TfR1; Trfr; T9; p90; CD antigen CD71 |
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| Gene, Accession # | Entrez: 7037; Uniprot: P02786 |
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| Catalog # | PA5-40261 |
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| Price | |
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| Order / More Info | Phospho-Transferrin Receptor (Ser24) Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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