| 产品详情 |
| Edit |   |
|---|
| Product Name | Recombinant Human Tumor necrosis factor ligand superfamily member 13B protein (TNFSF13B) (Active) |
|---|
| Description | Purity > 95% as determined by SDS-PAGE. MW: 14 & 59kDa. Full Length: 31-152aa & 153-692aa. C-terminal Avi-tagged. Homo sapiens (Human). Human Proprotein Convertase Subtilisin/Kexin Type 9 (PCSK9) is a secretory subtilase belonging to the proteinase K subfamily. PCSK9 is synthesized as a soluble zymogen that undergoes autocatalytic intramolecular processing in the ER, the pro domain and mature chain secrete together through noncovalent interactions. PCSK9 binds with low-density lipoprotein receptor (LDLR) and plays a major regulatory role in cholesterol homeostasis. Inhibition of PCSK9 function by preventing PCSK9/LDLR interaction is currently being explored as a means of lowering cholesterol levels. PCSK9 also binds to apolipoprotein receptor 2 (ApoER2), and play a role in the neural development. |
|---|
| Size | n/a |
|---|
| Concentration | n/a |
|---|
| Applications | RUO |
|---|
| Other Names | Proprotein Convertase Subtilisin/Kexin Type 9; Neural Apoptosis-Regulated Convertase 1; NARC-1; Proprotein Convertase 9; PC9; Subtilisin/Kexin-Like Protease PC9; PCSK9; NARC1 |
|---|
| Gene, Accession, CAS # | PCSK9, UniProt: Q8NBP7 |
|---|
| Catalog # | RPC27020 |
|---|
| Price | |
|---|
| Order / More Info | Recombinant Human Tumor necrosis factor ligand superfamily member 13B protein (TNFSF13B) (Active) from BIOMATIK |
|---|
| Product Specific References | n/a |
|---|
| 产品资料 |
|
|