产品详情 |
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Product Name | Floxuridine |
Description | Antineoplastic antimetabolite. Exhibits antiproliferative activity; inhibits thymidylate synthetase and disrupts DNA replication in human cells. Induces double-strand DNA breaks; activates ATR and ATM signaling pathways. Induces phosphorylation of Chk1 and Chk2 in OVCAR-8 and SKOV3ip ovarian cancer cell lines. Purity 98%. MW (observed): 246.19 |
Size | 50 mg |
Concentration | n/a |
Applications | n/a |
Other Names | 5-Fluoro-2'-deoxyuridine. FdUrd |
Gene, Accession, CAS # | CAS: 50-91-9 |
Catalog # | 4659/50 |
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Order / More Info | Floxuridine from TOCRIS BIOSCIENCE
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Product Specific References | PubMed: 21613406, 28442752 |
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