| 产品详情 |
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| Antigenic Specificity | SNAP alpha/beta |
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| Clone | 16D1 |
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| Host Species | Mouse |
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| Reactive Species | bovine, chicken, human, rat |
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| Isotype | IgG2b |
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| Format | purified |
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| Size | 100 µg |
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| Concentration | n/a |
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| Applications | Western Blot: 1:5,000 |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | SNAP alpha/beta Monoclonal Antibody (16D1). SNAPs (soluble NSF attachment proteins), acting in concert with SNAREs ( SNAP receptors) and the N-ethylmaleimide-sensitive fusion protein (NSF) are required for the fusion of transport vesicles to their target membranes in synaptic transmission, intra-Golgi transport, endosome-toendosome fusion and transcytotic vesicles-to-plasma membrane transport. Vesicle-to-target membrane docking (initial contact) occurs when the vesicle SNARE binds to its cognate target membrane SNARE. a-SNAP (or b-SNAP in brain) then binds to this docking complex and mediates the binding of NSF and thus the formation of a 20S fusion particle. It is thought that, once NSF is bound, ATP hydrolysis by NSF initiates the fusion |
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| Immunogen | n/a |
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| Other Names | NAPA, SNAP25, Synaptosomal-Associated Protein alpha/beta |
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| Gene, Accession # | Entrez: 100858304, 140673, 25012, 396444, 518407, 540853, 6616, 8775; Uniprot: P54920, P54921, P60878, P60880, P60881, P81125, Q17QQ3 |
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| Catalog # | MA1-12451 |
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| Price | |
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| Order / More Info | SNAP alpha/beta Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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