| 产品详情 |
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| Antigenic Specificity | TRBP |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | bovine, human, mouse, nonhuman primate, rat, zebrafish |
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| Isotype | n/a |
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| Format | purified |
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| Size | 100 µg |
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| Concentration | n/a |
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| Applications | Western Blot: 0.5-2 µg/mL |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | TRBP Polyclonal Antibody. TRBP belongs to the family of dsRNA-binding proteins. It consists of highly conserved 2 dsRNA-binding domains and C-terminal basic region. It is a unique cellular protein capable of binding to HIV-TAR RNA and stimulates expression of HIV-1 long terminal repeats. It also inhibits the host antiviral and anti-proliferative mechanisms by directly binding to IFN-regulated dsRNA-dependent protein kinase (PKR). TRBP associates with Ago2 protein and forms an integral component of Dicer-containing complex. It has a role in micro RNA processing and in RISC assembly. Other functions of TRBP include promoting cellular growth and tumorigenesis. |
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| Immunogen | n/a |
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| Other Names | TRBP2 |
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| Gene, Accession # | Entrez: 21357, 336141, 363006, 514674, 6895; Uniprot: P97473, Q0IIG6, Q15633, Q3SWU0, Q7SXR1 |
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| Catalog # | PA1-41109 |
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| Price | |
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| Order / More Info | TRBP Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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