| 产品详情 |
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| Antigenic Specificity | CD105 |
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| Clone | MEM-226 |
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| Host Species | Mouse |
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| Reactive Species | human |
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| Isotype | IgG2a |
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| Format | fluorescein (FITC) conjugate |
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| Size | 100 Tests |
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| Concentration | n/a |
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| Applications | Flow Cytometry: 20 µL/1x10^6 cells |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | CD105 Monoclonal Antibody (MEM-226), FITC. CD105 (Endoglin) is a homodimeric transmembrane glycoprotein serving in presence of TGFbetaR-2 as a receptor for TGFbeta-1 and TGFbeta-3. CD105 is highly expressed on endothelial cells and promotes angiogenesis during wound healing, infarcts and in a wide range of tumours and its gene expression is stimulated by hypoxia. CD105 prevents apoptosis in hypoxic endothelial cells and also antagonises the inhibitory effects of TGFbeta-1 on vascular endothelial cell growth and migration. Normal cellular levels of CD105 are required for formation of new blood vessels. |
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| Immunogen | n/a |
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| Other Names | CD105, END, HHT1, ORW, ORW1, CD105 antigen, ENG |
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| Gene, Accession # | Entrez: 2022; Uniprot: P17813 |
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| Catalog # | MA1-19594 |
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| Price | |
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| Order / More Info | CD105 Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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