| 产品详情 |
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| Antigenic Specificity | CD105 |
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| Clone | MJ7/18 |
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| Host Species | Rat |
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| Reactive Species | mouse |
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| Isotype | IgG2a, kappa |
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| Format | biotin conjugate |
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| Size | 100 ug |
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| Concentration | n/a |
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| Applications | Flow Cytometry: 0.5 µg/1x10^6 cells, Immunohistochemistry: Assay Dependent, Immunoprecipitation: Assay Dependent, Western Blot: Assay Dependent |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | CD105 Monoclonal Antibody (MJ7/18), Biotin. CD105 (Endoglin) is a homodimeric transmembrane glycoprotein serving in presence of TGFβR-2 as a receptor for TGFβ-1 and TGFβ-3. CD105 is highly expressed on endothelial cells and promotes angiogenesis during wound healing, infarcts and in a wide range of tumours and its gene expression is stimulated by hypoxia. CD105 prevents apoptosis in hypoxic endothelial cells and also antagonises the inhibitory effects of TGFβ-1 on vascular endothelial cell growth and migration. Normal cellular levels of CD105 are required for formation of new blood vessels. |
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| Immunogen | n/a |
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| Other Names | CD105, END, HHT1, ORW, ORW1, CD105 antigen, ENG |
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| Gene, Accession # | Entrez: 13805; Uniprot: Q63961 |
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| Catalog # | MA5-17944 |
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| Price | |
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| Order / More Info | CD105 Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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