| 产品详情 |
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| Product Name | BIO |
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| Description | Potent ATP-competitive glycogen synthase kinase-3 (GSK-3) inhibitor (IC50 = 5 nM). Also inhibits cyclin-dependent kinases (cdks; IC50 values are <100 nM for cdk2 and 5 and sub micromolar for cdk1, cdk4 and cdk9). Maintains self-renewal and pluripotency in embryonic stem cells via activation of the Wnt signaling pathway in vitro; also promotes proliferation and dedifferentiation in cardiomyocytes. Negative Control also available.. Purity 98%. MW (observed): 356.17 |
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| Size | 10 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | (2'Z,3'E)-6-Bromoindirubin-3'-oxime. 6BIO |
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| Gene, Accession, CAS # | CAS: 667463-62-9 |
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| Catalog # | 3194/10 |
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| Order / More Info | BIO from TOCRIS BIOSCIENCE
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| Product Specific References | PubMed: 22385965, 24263804, 24282277, 24779365, 25371059, 25402767, 25616418, 25637190, 25647637, 25860027, 26393419, 26542303, 27531891, 28416184 |
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