| 产品详情 |
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| Product Name | BIO 5192 |
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| Description | Highly selective and potent inhibitor of integrin α4β1 (Very Late Antigen-4; VLA-4) (Kd < 10 pM). Selectively binds α4β1 over a range of other integrins (IC50 values are 1.8, 138, 1053, > 500 and > 10,000 nM for α4β1, α9β1, α2β1, α4β7 and αIIbβ3, respectively). Induces a 30-fold increase in mobilization of murine hematopoietic stem and progenitor cells; displays a 3-fold additive effect with AMD 3100 (Cat. No. 3299). Decreases oxidative damage and improves neurological function following spinal cord injury in rats. Purity 98%. MW (observed): 817.78 |
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| Size | 10 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | (2S)-2-[[[(2S)-1-[(3,5-Dichlorophenyl)sulfonyl]-2-pyrrolidinyl]carbonyl]amino]-4-[[(2S)-4-methyl-2-[methyl[2-[4-[[[(2-methylphenyl)amino]carbonyl]amino]phenyl]acetyl]amino]-1-oxopentyl]amino]butanoic acid |
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| Gene, Accession, CAS # | CAS: 327613-57-0 |
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| Catalog # | 5051/10 |
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| Price | |
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| Order / More Info | BIO 5192 from TOCRIS BIOSCIENCE
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| Product Specific References | PubMed: 28712928 |
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