| 产品详情 |
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| Antigenic Specificity | Acetyl-p53 (Lys379) |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human, mouse |
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| Isotype | n/a |
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| Format | purified |
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| Size | 100 µL |
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| Concentration | n/a |
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| Applications | ChIP assay: 2 µL/10^6 cells, Immunocytochemistry: 1:100, Immunofluorescence: 1:100, Western Blot: 1:1000 |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Acetyl-p53 (Lys379) Polyclonal Antibody. The tumor suppressor protein, p53, is a sequence specific transcription factor that is activated by cellular stress. p53 mediates cell cycle arrest or apoptosis in response to DNA damage or starvation for pyrimidine nucleotides. p53 is up-regulated in response to stress signals and stimulated to activate transcription of specific genes, resulting in expression of p21waf1 and other proteins involved in G1 or G2/M arrest. The structure of p53 comprises an N-terminal transactivation domain, a central DNA-binding domain, an oligomerisation domain, and a C-terminal regulatory domain. There are various phosphorylation sites on p53, of which the phosphorylation at Ser15 is important for p53 activation and s |
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| Immunogen | n/a |
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| Other Names | OTTMUSP00000006194; cellular tumor antigen p53; p53 cellular tumor antigen; tumor suppressor p53; tumor supressor p53 |
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| Gene, Accession # | Entrez: 22059, 7157; Uniprot: P02340, P04637 |
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| Catalog # | PA5-17287 |
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| Price | |
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| Order / More Info | Acetyl-p53 (Lys379) Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | PubMed: 27799148 |
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