| 产品详情 |
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| Antigenic Specificity | CD205 |
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| Clone | PN-15 |
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| Host Species | Mouse |
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| Reactive Species | human, rat |
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| Isotype | IgG1, kappa |
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| Format | biotin conjugate |
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| Size | 500 µL |
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| Concentration | n/a |
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| Applications | Immunohistochemistry (Paraffin): 2-4 µg/mL, Western Blot: Assay Dependent |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | CD205 Monoclonal Antibody (PN-15), Biotin. CD205 (LY25, Lymphocyte Antigen 75) is an integral membrane glycoprotein involved in antigen uptake, trafficking and presentation that improves the induction of antigen-specific T cell immunity. CD205 is highly expressed by CD8+ dendritic cells (DCs) and also expressed at different levels by bone marrow Gr1+ cells, Langerhans cells, (BMDC) bone marrow derived DCs and thymic epithelial cells. CD205 acts as an endocytic receptor that directs captured antigens to the extracellular space towards a specialized antigen processing region. Further, CD205 also prompts the reduced proliferation of B lymphocytes. Diseases associated with CD205 dysfunction include pneumonic plague and lipid pneumonia. |
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| Immunogen | n/a |
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| Other Names | CA-IX, P54/58N, RCC-associated antigen G250, RCC-associated protein G250, carbonate dehydratase IX, carbonic anhydrase 9, carbonic dehydratase, membrane antigen MN, pMW1, renal cell carcinoma-associated antigen G250 |
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| Gene, Accession # | Entrez: 4065, 499800; Uniprot: O60449 |
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| Catalog # | MA5-13362 |
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| Price | |
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| Order / More Info | CD205 Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | PubMed: 18802156, 21630197, 22497861 |
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| 产品资料 |
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