| 产品详情 |
| Edit |   |
|---|
| Antigenic Specificity | CD205 |
|---|
| Clone | SPM487 |
|---|
| Host Species | Mouse |
|---|
| Reactive Species | human |
|---|
| Isotype | IgG1, kappa |
|---|
| Format | purified |
|---|
| Size | 1 mL |
|---|
| Concentration | n/a |
|---|
| Applications | Immunohistochemistry (Paraffin): 1:100 |
|---|
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
|---|
| Description | CD205 Monoclonal Antibody (SPM487). CD205 (LY25, Lymphocyte Antigen 75) is an integral membrane glycoprotein involved in antigen uptake, trafficking and presentation that improves the induction of antigen-specific T cell immunity. CD205 is highly expressed by CD8+ dendritic cells (DCs) and also expressed at different levels by bone marrow Gr1+ cells, Langerhans cells, (BMDC) bone marrow derived DCs and thymic epithelial cells. CD205 acts as an endocytic receptor that directs captured antigens to the extracellular space towards a specialized antigen processing region. Further, CD205 also prompts the reduced proliferation of B lymphocytes. Diseases associated with CD205 dysfunction include pneumonic plague and lipid pneumonia. |
|---|
| Immunogen | n/a |
|---|
| Other Names | gp200 |
|---|
| Gene, Accession # | Entrez: 4065; Uniprot: O60449 |
|---|
| Catalog # | MA1-38550 |
|---|
| Price | |
|---|
| Order / More Info | CD205 Antibody from INVITROGEN ANTIBODIES |
|---|
| Product Specific References | n/a |
|---|
| 产品资料 |
|
|