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| Antigenic Specificity | ANKRD28/PITK |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human |
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| Isotype | n/a |
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| Format | purified |
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| Size | 100 µL |
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| Concentration | n/a |
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| Applications | Immunohistochemistry: 1:100-1:500 |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | ANKRD28/PITK Polyclonal Antibody. Putative regulatory subunit of protein phosphatase 6 (PP6) that may be involved in the recognition of phosphoprotein substrates. Involved in the PP6-mediated dephosphorylation of NFKBIE opposing its degradation in response to TNF-alpha. Selectively inhibits the phosphatase activity of PPP1C. Targets PPP1C to modulate HNRPK phosphorylation. ANKRD28 selectively regulated phosphorylation of hnRNP-K at ser284, an effect that was enhanced in vivo by an S1013A/S1017A double mutant, suggesting that ANKRD28 targets PP1 in a regulated manner to dephosphorylate hnRNP-K selectively at ser284. |
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| Immunogen | n/a |
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| Other Names | KIAA0379 |
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| Gene, Accession # | Entrez: 23243; Uniprot: O15084 |
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| Catalog # | IHC-00522 |
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| Price | |
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| Order / More Info | ANKRD28/PITK Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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