产品详情 |
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Product Name | O-Desmethyl Gefitinib |
Description | A major active metabolite of gefitinib in human plasma; inhibits EGFR in subcellular assays similarly to gefitinib (IC50s = 36 and 22 nM, respectively); less active than gefitinib in whole cell assays (IC50s = 760 and 49 nM, respectively); does not reduce tumor growth as well as gefitinib in a LoVo tumor mouse xenograft model, |
Size | 5 mg |
Concentration | n/a |
Applications | n/a |
Other Names | CYP450 2D6 endothelial growth factor receptor M523595 M-523595 |
Gene, Accession, CAS # | CAS: 847949-49-9 |
Catalog # | 22365-5 |
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Order / More Info | O-Desmethyl Gefitinib from CAYMAN CHEMICAL COMPANY |
Product Specific References | n/a |
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