| 产品详情 |
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| Antigenic Specificity | Bcl-10 |
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| Clone | 4F8 |
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| Host Species | Mouse |
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| Reactive Species | human, mouse |
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| Isotype | IgG1 |
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| Format | purified |
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| Size | 100 µg |
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| Concentration | n/a |
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| Applications | Flow Cytometry: 1/200 - 1/400, Immunocytochemistry: 1:200-1:1000, Immunofluorescence: 1/200 - 1/1000, Immunohistochemistry: 1/200 - 1/1000, Western Blot: 1/500 - 1/2000 |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Bcl-10 Monoclonal Antibody (4F8). BCL-10 is an N-terminal CARD (Caspase Recruitment Domain) containing protein that is involved in the adaptive immune response. It promotes apoptosis, pro-caspase-9 maturation, and activation of NF-kappa-B via NIK and IKK. BCL-10 is also an adapter protein between upstream TNFR1-TRADD-RIP complex and the downstream NIK-IKK-IKAP complex. It is a substrate for MALT1. Mutations in the gene can lead to Immmunodeficiency 37 or Lymphoma, mucosa-associated lymphoid type. |
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| Immunogen | n/a |
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| Other Names | CLAP; mE10; CIPER; c-E10; CARMEN; BCL10 |
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| Gene, Accession # | Entrez: 12042, 8915; Uniprot: O95999, Q9Z0H7 |
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| Catalog # | MA5-14756 |
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| Price | |
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| Order / More Info | Bcl-10 Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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| 产品资料 |
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