| 产品详情 |
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| Antigenic Specificity | Bcl-10 |
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| Clone | E.177.7 |
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| Host Species | Rabbit |
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| Reactive Species | human, mouse, nonhuman primate, rat |
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| Isotype | IgG |
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| Format | purified |
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| Size | 100 µL |
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| Concentration | n/a |
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| Applications | Immunoprecipitation: 1:50, Western Blot: 1:1000 |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Bcl-10 Monoclonal Antibody (E.177.7). BCL-10 is an N-terminal CARD (Caspase Recruitment Domain) containing protein that is involved in the adaptive immune response. It promotes apoptosis, pro-caspase-9 maturation, and activation of NF-kappa-B via NIK and IKK. BCL-10 is also an adapter protein between upstream TNFR1-TRADD-RIP complex and the downstream NIK-IKK-IKAP complex. It is a substrate for MALT1. Mutations in the gene can lead to Immmunodeficiency 37 or Lymphoma, mucosa-associated lymphoid type. |
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| Immunogen | n/a |
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| Other Names | B-cell lymphoma/leukemia 10; CARD containing molecule enhancing NF-kB; CARD-containing apoptotic signaling protein; CARD-containing molecule enhancing NF-kappa-B; CARD-containing proapoptotic protein; CED-3/ICH-1 prodomain homologous E10-like regulator; OTTHUMP00000011647; OTTHUMP00000036080; bcl-10; cCARMEN; caspase-recruiting domain-containing protein; cellular homolog of vCARMEN; cellular-E10; hCLAP; mammalian CARD-containing adapter molecule E10 |
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| Gene, Accession # | Entrez: 12042, 83477, 8915; Uniprot: O95999, Q9QYN5, Q9Z0H7 |
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| Catalog # | MA5-14878 |
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| Price | |
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| Order / More Info | Bcl-10 Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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