| 产品详情 |
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| Antigenic Specificity | BABAM1 |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human |
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| Isotype | n/a |
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| Format | purified |
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| Size | 400 µl |
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| Concentration | n/a |
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| Applications | Flow Cytometry: 1:10-1:50, Immunohistochemistry (Paraffin): 1:50-1:100, Western Blot: 1:1000 |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | BABAM1 Polyclonal Antibody. Component of the BRCA1-A complex, a complex that specifically recognizes 'Lys-63'-linked ubiquitinated histones H2A and H2AX at DNA lesions sites, leading to target the BRCA1-BARD1 heterodimer to sites of DNA damage at double-strand breaks (DSBs). The BRCA1-A complex also possesses deubiquitinase activity that specifically removes 'Lys-63'-linked ubiquitin on histones H2A and H2AX. In the BRCA1-A complex, it is required for the complex integrity and its localization at DSBs. Probably also plays a role as a component of the BRISC complex, a multiprotein complex that specifically cleaves 'Lys-63'-linked ubiquitin. In these 2 complexes, it is probably required to maintain the stability of BRE/BRCC45 and help the 'Ly |
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| Immunogen | n/a |
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| Other Names | BRISC and BRCA1-A complex member 1, Mediator of RAP80 interactions and targeting subunit of 40 kDa, New component of the BRCA1-A complex, BABAM1, C19orf62, MERIT40, NBA1 |
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| Gene, Accession # | Entrez: 29086; Uniprot: Q9NWV8 |
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| Catalog # | PA5-49611 |
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| Price | |
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| Order / More Info | BABAM1 Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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