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| Antigenic Specificity | Ly-49A/D |
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| Clone | eBio12A8 (12A8) |
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| Host Species | Rat |
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| Reactive Species | mouse |
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| Isotype | IgG2a, kappa |
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| Format | phycoerythrin (PE) conjugate |
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| Size | 50 µg |
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| Concentration | n/a |
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| Applications | Flow Cytometry: 0.125 µg/test |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Ly-49A/D Monoclonal Antibody (eBio12A8 (12A8)), PE, eBioscience™. The Ly-49 family of NK-cell receptors, members of the C-type lectin superfamily, are disulfide-linked type-II transmembrane protein homodimers with extracellular carbohydrate-recognition domains which bind to MHC class I alloantigens. The Ly-49 family members are expressed independently, such that an individual NK or T cell may display more than one class of Ly-49 receptor homodimers. Ly-49D is expressed on subsets of natural killer cells in C57BL/6, C3H/He, and SJL mice, but not DBA/2, AKR, CBA/J, or BALB/c mice. The Ly-49D antigen has not been detected on NK-1.1+ T cells. The Ly-49D receptor has been implicated in mediation of NK cell cytolysis. Ly-49D is an activatin |
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| Immunogen | n/a |
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| Other Names | n/a |
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| Gene, Accession # | Entrez: 16627, 16635; Uniprot: P20937, Q60651 |
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| Catalog # | 12-5783-81 |
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| Price | |
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| Order / More Info | Ly-49A/D Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | PubMed: 21518798, 25392524 |
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