| 产品详情 |
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| Antigenic Specificity | RIG-I |
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| Clone | 35H2L48 |
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| Host Species | Recombinant Rabbit |
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| Reactive Species | human, mouse |
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| Isotype | IgG |
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| Format | purified |
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| Size | 100 µg |
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| Concentration | n/a |
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| Applications | Immunocytochemistry: 5 µg/mL, Immunofluorescence: 5 µg/mL, Immunohistochemistry (Paraffin): 1:20, Western Blot: 1 µg/mL |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | RIG-I Antibody (35H2L48), ABfinity™ Rabbit Monoclonal. Retinoic acid-inducible gene I, RIG-I is a pattern recognition receptor (PRR) involved in the recognition of viral dsRNA. Along with MDA5, RIG-I detects viral dsRNA and activates the innate immune response. Both MDA5 and RIG-I are RNA helicases and they perform overlapping as well as distinct roles. RIG-I is activated by dsRNAs without a 5'-triphosphate end and short dsRNAs, whereas MDA5 is activated by long dsRNAs. Once activated, both proteins signal through IPS-1 activating transcription factors NF-kappaB and IRF-3 (1) and ultimately activating apoptosis, cytokine signaling, and inflammation. RIG-I is essential for signaling by influenza A, influenza B, human respiratory syncyt |
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| Immunogen | n/a |
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| Other Names | Probable ATP-dependent RNA helicase DDX58, DEAD-box protein 58, Retinoic acid-inducible gene 1 protein, RIG-1, RIG-I, DDX58, |
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| Gene, Accession # | Entrez: 230073, 23586; Uniprot: O95786, Q6Q899 |
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| Catalog # | 700366 |
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| Price | |
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| Order / More Info | RIG-I Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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