| 产品详情 |
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| Antigenic Specificity | RIG-I |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human, nonhuman primate |
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| Isotype | n/a |
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| Format | purified |
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| Size | 100 ug |
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| Concentration | n/a |
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| Applications | Immunohistochemistry (Paraffin): 5-10 µg/mL, Western Blot: 2-4 µg/mL |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | RIG-I Polyclonal Antibody. RIG-I belongs to the Helicase family and contains two CARD domains, one helicase ATP-binding domain and one helicase C-terminal domain. It is involved in innate immune defense against viruses. It triggers a transduction cascade involving MAVS/IPS1 which leads to activation of NF-kappa-B, IRF3 and IRF7 inducing expression of antiviral cytokines such as INF-beta and RANTES (CCL5) during viral replication. Reports also says that TLR3 and RIG-like receptor on myeloid dendritic cells and Rig-like receptor on human NK cells are both required for production of IFN-gamma in response to double-stranded RNA during viral infection. |
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| Immunogen | n/a |
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| Other Names | RIG-I, DEAD box protein 58, DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide, RIG-1, RNA helicase RIG-I, probable ATP-dependent RNA helicase DDX58, retinoic acid inducible gene I, retinoic acid-inducible gene 1 protein, retinoic acid-inducible gene I protein |
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| Gene, Accession # | Entrez: 23586; Uniprot: O95786 |
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| Catalog # | PA5-23497 |
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| Price | |
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| Order / More Info | RIG-I Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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