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Product Name | Recombinant Bovine coronavirus Spike glycoprotein (S), partial |
Description | Purity > 85% as determined by SDS-PAGE. MW: 27.2kDa. Partial: 326-540aa. N-terminal 10xHis-tagged. Bovine coronavirus (strain Mebus) (BCoV) (BCV). S1 attaches the virion to the cell membrane by binding to 9-O-acetylated sialic acid containing proteins, initiating the infection. S2 is a class I viral fusion protein. Under the current model, the protein has at least 3 conformational states: pre-fusion native state, pre-hairpin intermediate state, and post-fusion, the coiled coil regions (heptad repeats) assume a trimer-of-hairpins structure, positioning the fusion peptide in close proximity to the C-terminal region of the ectodomain. The formation of this structure appears to drive apposition and subsequent fusion of viral and target cell membranes |
Size | 100ug |
Concentration | n/a |
Applications | RUO |
Other Names | E2; Peplomer protein |
Gene, Accession, CAS # | S, UniProt: P15777 |
Catalog # | RPC22452 |
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Order / More Info | Recombinant Bovine coronavirus Spike glycoprotein (S), partial from BIOMATIK |
Product Specific References | n/a |
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