| 产品详情 |
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| Antigenic Specificity | B-Raf |
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| Clone | H.600.2 |
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| Host Species | Rabbit |
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| Reactive Species | human, mouse, nonhuman primate, rat |
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| Isotype | IgG |
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| Format | purified |
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| Size | 100 µL |
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| Concentration | n/a |
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| Applications | Western Blot: 1:1000 |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | B-Raf Monoclonal Antibody (H.600.2). This gene encodes a protein belonging to the raf/mil family of serine/threonine protein kinases. This protein plays a role in regulating the MAP kinase/ERKs signaling pathway, which affects cell division, differentiation, and secretion. Mutations in this gene are associated with cardiofaciocutaneous syndrome, a disease characterized by heart defects, mental retardation and a distinctive facial appearance. Mutations in this gene have also been associated with various cancers, including non-Hodgkin lymphoma, colorectal cancer, malignant melanoma, thyroid carcinoma, non-small cell lung carcinoma, and adenocarcinoma of lung. A pseudogene, which is located on chromosome X, has been identified for this gene. |
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| Immunogen | n/a |
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| Other Names | 94 kDa B-raf protein; B-Raf proto-oncogene serine/threonine-protein kinase (p94); murine sarcoma viral (v-raf) oncogene homolog B1; p94; proto-oncogene B-Raf; serine/threonine-protein kinase B-raf |
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| Gene, Accession # | Entrez: 109880, 114486, 673; Uniprot: P15056, P28028 |
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| Catalog # | MA5-15000 |
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| Price | |
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| Order / More Info | B-Raf Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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| 产品资料 |
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