| 产品详情 |
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| Antigenic Specificity | B-Raf |
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| Clone | RM8 |
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| Host Species | Rabbit |
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| Reactive Species | human |
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| Isotype | IgG |
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| Format | purified |
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| Size | 100 µg |
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| Concentration | n/a |
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| Applications | Immunocytochemistry: 2-10 µg/mL, Immunofluorescence: 2-10 µg/mL, Immunohistochemistry: 2-10 µg/mL, Western Blot: 0.5-2 µg/mL |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | B-Raf Monoclonal Antibody (RM8). B-raf belongs to the raf/mil family of serine/threonine protein kinases. This protein plays a role in regulating the MAP kinase/ERKs signaling pathway, which affects cell division, differentiation, and secretion. Mutations in the gene are associated with cardiofaciocutaneous syndrome, a disease characterized by heart defects, mental retardation and a distinctive facial appearance. Mutations in this gene have also been associated with various cancers, including non-Hodgkin lymphoma, colorectal cancer, malignant melanoma, thyroid carcinoma, non-small cell lung carcinoma, and adenocarcinoma of lung. A pseudogene, which is located on chromosome X, has been identified for this gene. |
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| Immunogen | n/a |
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| Other Names | n/a |
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| Gene, Accession # | Entrez: 673; Uniprot: P15056 |
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| Catalog # | MA5-24661 |
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| Price | |
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| Order / More Info | B-Raf Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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