| 产品详情 |
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| Antigenic Specificity | CD41a |
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| Clone | eBioMWReg30 (MWReg30) |
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| Host Species | Rat |
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| Reactive Species | mouse |
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| Isotype | IgG1, kappa |
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| Format | eFluor 450 conjugate |
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| Size | 25 µg |
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| Concentration | n/a |
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| Applications | Flow Cytometry: 0.5 µg/test |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | CD41a Monoclonal Antibody (eBioMWReg30 (MWReg30)), eFluor 450, eBioscience™. CD41 (platelet glycoprotein IIb, ITGA2B) is composed of two subunits -120 kDa a, alpha and 23 kDa b, beta- that interact with CD61 in the presence of calcium to form a functional adhesive protein receptor. CD41 is also involved in blood coagulation by mediating platelet aggregation. Upon blood vessel damage, CD41 binds to a variety of proteins including von Willebrand factor, fibrinogen, fibronectin and vitronectin. CD41 is mainly expressed on megakaryocyte-platelet lineage, but generally belongs to the antigens that are expressed during the early stages of hematopoietic differentiation. Diseases associated with CD41 dysfunction include Glansmann Thrombasthen |
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| Immunogen | n/a |
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| Other Names | BDPLT2, CD41, CD41B, GP2B, GPIIb, GT, GTA, HPA3, GPalpha IIb, integrin alpha-IIb, platelet fibrinogen receptor, alpha subunit, platelet membrane glycoprotein IIb, platelet-specific antigen BAK, ITGA2B |
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| Gene, Accession # | Entrez: 16399; Uniprot: Q9QUM0 |
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| Catalog # | 48-0411-80 |
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| Price | |
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| Order / More Info | CD41a Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | PubMed: 10397735, 21989919, 22628281, 22996659, 23133375, 23940756, 24162846, 24407241, 24829209, 25139854, 25474413, 25824689, 26293303, 26527618, 26891705, 26912146, 27250641, 27428424, 27453007, 27689744, 27869129, 28218906, 28486541, 28963568, 29239838, 29361560, 29555020, 29625072 |
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