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Product Name | TPA, Human Recombinant (Sf9) |
Description | Tissue plasminogen activator (PLAT or tPA) is a secreted serine protease which converts the proenzyme plasminogen to plasmin, a fibrinolytic enzyme. Plasminogen is synthesized as a single chain which is cleaved by PLAT into the two chain disulfide linked plasmin. This enzyme plays a role in cell migration and tissue remodeling. Increased enzymatic activity causes hyperfibrinolysis, which manifests as excessive bleeding; decreased activity leads to hypofibrinolysis which can result in thrombosis or embolism. tPA Human Recombinant produced in Sf9 Baculovirus cells is a single, glycosylated polypeptide chain containing 545 amino acids (24-562 a.a) and having a molecular mass of 61.3 kDa (Molecular size on SDS-PAGE will appear at approximately |
Size | 50 µg |
Concentration | n/a |
Applications | RUO |
Other Names | Tissue-type plasminogen activator, EC 3.4.21.68, tPA, t-PA, t-plasminogen activator, TPA, T-PA, DKFZp686I03148, PLAT and tPA. |
Gene, Accession, CAS # | PLAT, Accession: P00750 |
Catalog # | P1325-50 |
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Order / More Info | TPA, Human Recombinant (Sf9) from BIOVISION, INC. |
Product Specific References | n/a |
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