| 产品详情 |
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| Antigenic Specificity | EFCAB4B |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human, mouse |
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| Isotype | n/a |
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| Format | purified |
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| Size | 100 ug |
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| Concentration | n/a |
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| Applications | Immunocytochemistry: 20 µg/mL, Immunofluorescence: 20 µg/mL, Immunohistochemistry: 10 µg/mL, Western Blot: 1 µg/mL |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | EFCAB4B Polyclonal Antibody. EFCAB4B, also known as Calcium release-activated calcium channel regulator 2A, is a novel Ca2+-binding EF-hand protein that is thought to play a key role in store-operated Ca2+ entry in T-cells by regulating CRAC channel activation. EFCAB4B acts as a cytoplasmic calcium-sensor that forms a complex with ORAI1 and STIM1 at the junctional regions between the plasma membrane and the endoplasmic reticulum upon low Ca2+ concentration. A closely related protein, EFCAB4A, is likely to play a similar role as EFCAB4B, but the detailed function of EFCAB4A is still under investigation. |
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| Immunogen | n/a |
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| Other Names | CRACR2A; CRAC channel regulator 2A; EF-hand calcium-binding domain-containing protein 4B; calcium release-activated calcium channel regulator 2A |
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| Gene, Accession # | Entrez: 381812, 84766; Uniprot: Q3UP38, Q9BSW2 |
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| Catalog # | PA5-21060 |
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| Price | |
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| Order / More Info | EFCAB4B Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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