| 产品详情 |
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| Antigenic Specificity | EFHD2 |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human, mouse, rat |
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| Isotype | n/a |
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| Format | purified |
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| Size | 100 ug |
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| Concentration | n/a |
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| Applications | Immunocytochemistry: 20 µg/mL, Immunofluorescence: 20 µg/mL, Immunohistochemistry: 5 µg/mL, Western Blot: 1-2 µg/mL |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | EFHD2 Polyclonal Antibody. EFHD2, also known as Swiprosin-1 or SWS1, is an EF-hand and coiled-coil-containing adaptor protein that plays a role in lymphocyte physiology. EFHD2 exhibits the highest expression in CD8+ T cells and immature B cells. It provides a membrane scaffold that is required for the Syk-, SLP-65-, and PLC-gamma2-dependent B-cell receptor (BCR)-induced calcium flux. EFHD2 may also regulate BCR-induced immature and primary B-cell apoptosis. It controls spontaneous apoptosis through the regulation of BCL2L1 abundance. Also, EFHD2 plays a role as negative regulator of the canonical NF-kappa-B-activating branch. |
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| Immunogen | n/a |
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| Other Names | RP3-467K16.3, SWS1; EF hand domain containing 2; EF hand domain family, member D2; EF-hand domain-containing protein D2; swiprosin 1; swiprosin-1 |
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| Gene, Accession # | Entrez: 27984, 298609, 79180; Uniprot: Q4FZY0, Q96C19, Q9D8Y0 |
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| Catalog # | PA5-20919 |
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| Price | |
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| Order / More Info | EFHD2 Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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