| 产品详情 |
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| Antigenic Specificity | NUP214 |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human, mouse |
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| Isotype | n/a |
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| Format | purified |
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| Size | 100 µL |
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| Concentration | n/a |
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| Applications | Western Blot: 1:1,000 |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | NUP214 Polyclonal Antibody. Calcineurin is a widely distributed Ser/Thr, calcium and calmodulin-dependent protein phosphatase. It mediates the immunosuppressive actions of drugs such as FK506 and cyclosporin, and has also been implicated in a number of calcium-sensitive pathways in the nervous system. Calcineurin has been found to be associated with other proteins, such as calmodulin, FKBP12, the ryanodine receptor, inositol 1,4,5-trisphosphate, and a recently identified protein, calcineurin inhibitor (cain). Cain has been shown to bind calcineurin through its C-terminal tail. Recent studies have shown cain to bind to both amphiphysin 1 and calcineurin simultaneously and therefore acts as a physiological inhibitor of calcineurin. The bindin |
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| Immunogen | n/a |
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| Other Names | Calcineurin Inhibitor |
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| Gene, Accession # | Entrez: 227720, 8021; Uniprot: P35658, Q80U93 |
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| Catalog # | A300-717A-M |
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| Price | |
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| Order / More Info | NUP214 Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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