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Product Name | FYVE, RhoGEF and PH Domain Containing 1 (FGD1) peptide |
Description | FGD1 contains Dbl (DH) and pleckstrin (PH) homology domains. It can bind specifically to the Rho family GTPase Cdc42Hs and stimulate the GDP-GTP exchange of the isoprenylated form of Cdc42Hs. It also stimulates the mitogen activated protein kinase cascade leading to c-Jun kinase SAPK/JNK1 activation. FGD1 has an essential role in embryonic development, and FGD1 gene mutations result in the human developmental disorder, Aarskog-Scott syndrome.FGD1 contains Dbl (DH) and pleckstrin (PH) homology domains. It can bind specifically to the Rho family GTPase Cdc42Hs and stimulate the GDP-GTP exchange of the isoprenylated form of Cdc42Hs. |
Size | 100 µg |
Concentration | n/a |
Applications | Western Blotting (WB),Immunohistochemistry (IHC),Blocking Peptide (BP) |
Other Names | AAS|FGDY|MRXS16|ZFYVE3 |
Gene, Accession, CAS # | n/a |
Catalog # | ABIN939123 |
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Order / More Info | FYVE, RhoGEF and PH Domain Containing 1 (FGD1) peptide from ANTIBODIES-ONLINE GmbH |
Product Specific References | n/a |
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