| 产品详情 |
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| Product Name | Isosilybin |
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| Description | A flavanolignan with antioxidant and anticancer activities; inhibits lipid peroxidation in rat liver microsomes (IC50 = 32 µM); inhibits the production of ROS, MDA and LDH release, and reduction in total antioxidant capacity induced by Aβ25-35 in HT-22 hippocampal cells; increases protein and mRNA expression of HO-1, GST, AKCR1C1, and AKCR1C2 in HT-22 cells; reduces tumor volume and increases tumor cell apoptosis in a DU145 prostate cancer mouse xenograft model at 50 and 100 mg/kg; reduces expression of tumor angiogenesis markers CD31, nestin, VEGF, VEGFR1, VEGFR2, phosphor-Akt, and HIF-1α in tumor tissue without reducing blood vessel count in non-cancerous liver, lung, and kidney tissue in DU145 tumor bearing mice, |
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| Size | 1 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | Isosilibinin|Isosilybinin|Silybin B |
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| Gene, Accession, CAS # | CAS: 72581-71-6 |
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| Catalog # | 24913-1 |
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| Price | |
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| Order / More Info | Isosilybin from CAYMAN CHEMICAL COMPANY |
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| Product Specific References | n/a |
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| 产品资料 |
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