| 产品详情 |
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| Antigenic Specificity | ID3 |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human, mouse, rat |
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| Isotype | n/a |
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| Format | purified |
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| Size | 100 µl |
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| Concentration | n/a |
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| Applications | Immunohistochemistry (Paraffin): 1:50-1:200 |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | ID3 Polyclonal Antibody. Members of the Id family of basic helix-loop-helix (bHLH) proteins include ID1, ID2, ID3 and ID4. They are ubiquitously expressed and dimerize with members of the class A and B HLH proteins. Due to the absence of the basic region, the resulting heterodimers cannot bind DNA. The ID-type proteins thus appear to negatively regulate DNA binding of bHLH proteins. Since ID1 inhibits DNA binding of E12 and Myo D, it apparently functions to inhibit muscle-specific gene expression. Under conditions that facilitate muscle cell differentiation, the ID protein levels fall, allowing E12 and/or E47 to form heterodimers with Myo D and myogenin, which in turn activate myogenic differentiation. It has been shown that expression of e |
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| Immunogen | n/a |
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| Other Names | HEIR-1, bHLHb25 |
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| Gene, Accession # | Entrez: 15903, 25585, 3399; Uniprot: P41133, P41138, Q02535 |
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| Catalog # | PA5-50683 |
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| Price | |
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| Order / More Info | ID3 Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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