| 产品详情 |
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| Antigenic Specificity | Phospho-GluR1 (Ser845) |
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| Clone | RM296 |
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| Host Species | Rabbit |
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| Reactive Species | human, mouse, rat |
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| Isotype | IgG |
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| Format | purified |
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| Size | 100 µl |
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| Concentration | n/a |
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| Applications | Immunohistochemistry: 1:500-1:1000, Western Blot: 1:1000-1:2000 |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Phospho-GluR1 (Ser845) Monoclonal Antibody (RM296). GluR1 (glutamate receptor 1) is an ionotropic glutamate receptor. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system. Binding of the excitatory neurotransmitter, L-glutamate, induces a conformation change that leads to the opening of the cation channel and converts the chemical signal to an electrical impulse. Then, the receptor desensitizes rapidly and enters a transiet inactive state characterized by the presence of a bound agonist. In the presence of CACNG4, CACNG7, or CACNG8 GluR1 shows resensitization which is characterized by a delayed accumulation of current flux upon continued application of glutamate. |
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| Immunogen | n/a |
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| Other Names | n/a |
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| Gene, Accession # | Entrez: 14799, 2890, 50592; Uniprot: P19490, P23818, P42261 |
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| Catalog # | MA5-27975 |
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| Price | |
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| Order / More Info | Phospho-GluR1 (Ser845) Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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