| 产品详情 |
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| Antigenic Specificity | FAM193B |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human |
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| Isotype | n/a |
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| Format | purified |
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| Size | 100 ug |
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| Concentration | n/a |
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| Applications | Immunocytochemistry: 20 µg/mL, Immunofluorescence: 20 µg/mL, Western Blot: 1 µg/mL |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | FAM193B Polyclonal Antibody. FAM193B, also known as IRIZIO, was initially identified as a protein that is upregulated in alveolar rhabdomyosarcoma (ARMS), a type of fast-growing tumor characterized by chromosomal translocations fusing the PAX3 or PAX7 gene with that of FOXO1. It has been suggested that, in addition to the PAX3-FOXO1 gene fusion, disruption of the Rb and p53 pathways is required for full ARMS tumorigenesis. In PAX3-FOXO1-expressing primary mouse fibroblasts that possessed a defective p53 pathway, FAM193B expression enabled the tumorigenic transformation, suggesting that FAM193B may contribute to rhabdomyosarcomagenesis in humans. |
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| Immunogen | n/a |
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| Other Names | FAM193B, Family with sequence similarity 193 member B, IRIZIO |
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| Gene, Accession # | Entrez: 54540; Uniprot: Q96PV7 |
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| Catalog # | PA5-34440 |
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| Price | |
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| Order / More Info | FAM193B Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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