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| Antigenic Specificity | Phospho-LIMK1/LIMK2 (Thr508, Thr505) |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human, mouse, rat |
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| Isotype | n/a |
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| Format | purified |
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| Size | 100 µg |
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| Concentration | n/a |
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| Applications | Immunohistochemistry (Paraffin): 1:50-1:100, Western Blot: 1:500-1:1000 |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Phospho-LIMK1/LIMK2 (Thr508, Thr505) Polyclonal Antibody. Proteins containing LIM motifs are typically involved in cell fate determination and growth control. A family of proteins designated LIM kinases, including LIMK-1 and LIMK-2, has been identified. LIMK-1 has been shown to regulate the stabilization of F-Actin structures and cofilin activity, indicating that LIMK-1 plays a role in a signaling pathway involved in the regulation of cell motility and morphogenesis. LIMK-1 inhibits neuronal differentiation of PC12 cells, and is thought to act by interfering with events downstream of MAPK activation. Expression patterns of LIMK-1 and LIMK-2 suggest that these proteins may have different functions during development. A truncated form of LIMK |
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| Immunogen | n/a |
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| Other Names | LIM domain kinase 1, LIMK-1, LIMK1, LIMK, LIM domain kinase 2, LIMK 2, LIMK2 |
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| Gene, Accession # | Entrez: 16885, 16886, 29524, 3984, 3985, 65172; Uniprot: O54785, P53667, P53668, P53669, P53670, P53671 |
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| Catalog # | PA5-38078 |
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| Price | |
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| Order / More Info | Phospho-LIMK1/LIMK2 (Thr508, Thr505) Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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