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| Antigenic Specificity | GATSL3 |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human |
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| Isotype | n/a |
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| Format | purified |
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| Size | 100 µL |
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| Concentration | n/a |
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| Applications | Western Blot: 1:500-1:3000 |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | GATSL3 Polyclonal Antibody. GATSL3 functions as an intracellular arginine sensor within the amino acid-sensing branch of the TORC1 signaling pathway. As a homodimer or a heterodimer with CASTOR2, binds and inhibits the GATOR subcomplex GATOR2 and thereby mTORC1. Binding of arginine to CASTOR1 allosterically disrupts the interaction of CASTOR1-containing dimers with GATOR2 which can in turn activate mTORC1 and the TORC1 signaling pathway. |
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| Immunogen | n/a |
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| Other Names | GATS protein-like 3 |
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| Gene, Accession # | Entrez: 652968; Uniprot: Q8WTX7 |
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| Catalog # | PA5-78683 |
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| Price | |
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| Order / More Info | GATSL3 Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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