| 产品详情 |
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| Antigenic Specificity | RRM1 |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | bovine, canine, chicken, human, mouse, nonhuman primate, rat, Xenopus laevis |
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| Isotype | n/a |
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| Format | purified |
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| Size | 100 µL |
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| Concentration | n/a |
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| Applications | Western Blot: 1:1000 |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | RRM1 Polyclonal Antibody. This gene encodes one of two non-identical subunits that constitute ribonucleoside-diphosphate reductase, an enzyme essential for the production of deoxyribonucleotides prior to DNA synthesis in S phase of dividing cells. It is one of several genes located in the imprinted gene domain of 11p15.5, an important tumor-suppressor gene region. Alterations in this region have been associated with the Beckwith-Wiedemann syndrome, Wilms tumor, rhabdomyosarcoma, adrenocrotical carcinoma, and lung, ovarian, and breast cancer. This gene may play a role in malignancies and disease that involve this region. |
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| Immunogen | n/a |
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| Other Names | ribonucleoside-diphosphate reductase large subunit; ribonucleoside-diphosphate reductase subunit M1; ribonucleotide reductase M1 polypeptide; ribonucleotide reductase large subunit; ribonucleotide reductase, R1 subunit; ribonucleotide reductase, large subunit |
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| Gene, Accession # | Entrez: 20133, 399431, 419081, 476823, 505537, 6240, 685579; Uniprot: P07742, P23921 |
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| Catalog # | PA5-17023 |
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| Price | |
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| Order / More Info | RRM1 Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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