| 产品详情 |
| Edit |   |
| Antigenic Specificity | RRM1 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse |
| Isotype | n/a |
| Format | purified |
| Size | 100 µL |
| Concentration | n/a |
| Applications | Immunocytochemistry: 1:100-1:1000, Immunofluorescence: 1:100-1:1000, Immunohistochemistry (Paraffin): 1:100-1:1000, Western Blot: 1:500-1:3000 |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | RRM1 Polyclonal Antibody. This gene encodes one of two non-identical subunits that constitute ribonucleoside-diphosphate reductase, an enzyme essential for the production of deoxyribonucleotides prior to DNA synthesis in S phase of dividing cells. It is one of several genes located in the imprinted gene domain of 11p15.5, an important tumor-suppressor gene region. Alterations in this region have been associated with the Beckwith-Wiedemann syndrome, Wilms tumor, rhabdomyosarcoma, adrenocrotical carcinoma, and lung, ovarian, and breast cancer. This gene may play a role in malignancies and disease that involve this region. |
| Immunogen | n/a |
| Other Names | R1, RIR1, RR1, ribonucleoside-diphosphate reductase large subunit, ribonucleoside-diphosphate reductase subunit M1, ribonucleotide reductase M1 polypeptide, ribonucleotide reductase, R1 subunit, ribonucleotide reductase, large subunit |
| Gene, Accession # | Entrez: 20133, 6240; Uniprot: P07742, P23921 |
| Catalog # | PA5-27263 |
| Price | |
| Order / More Info | RRM1 Antibody from INVITROGEN ANTIBODIES |
| Product Specific References | n/a |
| 产品资料 |
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