| 产品详情 |
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| Antigenic Specificity | HPK1 |
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| Clone | 2A1 |
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| Host Species | Mouse |
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| Reactive Species | human |
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| Isotype | IgG1, lambda |
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| Format | purified |
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| Size | 100 µL |
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| Concentration | n/a |
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| Applications | Immunocytochemistry: 1:250, Immunofluorescence: 1:250, Immunoprecipitation: 3 µL, Western Blot: 2 µg/mL |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | HPK1 Monoclonal Antibody (2A1). The c-Jun amino-terminal kinases (JNKs)/stress-activated protein kinases (SAPKs) play a crucial role in stress responses in mammalian cells. The mechanism underlying this pathway in the hematopoietic system is unclear, but it is a key in understanding the molecular basis of blood cell differentiation. We have cloned a novel protein kinase, termed hematopoietic progenitor kinase 1 (HPK1), that is expressed predominantly in hematopoietic cells, including early progenitor cells. HPK1 is related distantly to the p21(Cdc42/Rac1)-activated kinase (PAK) and yeast STE20 implicated in the mitogen-activated protein kinase (MAPK) cascade. Expression of HPK1 activates JNK1 specifically, and it elevates strongly AP-1-medi |
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| Immunogen | n/a |
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| Other Names | HPK1 |
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| Gene, Accession # | Entrez: 11184; Uniprot: Q92918 |
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| Catalog # | LF-MA0211 |
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| Price | |
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| Order / More Info | HPK1 Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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