| Edit |   |
|---|
| Antigenic Specificity | Podocin |
|---|
| Clone | polyclonal |
|---|
| Host Species | Rabbit |
|---|
| Reactive Species | human |
|---|
| Isotype | n/a |
|---|
| Format | purified |
|---|
| Size | 100 µl |
|---|
| Concentration | n/a |
|---|
| Applications | Immunohistochemistry: 1:500-1:1000 |
|---|
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
|---|
| Description | Podocin Polyclonal Antibody. The pathological conditions of SRN1 correlate well with mutations at the NPHS2 gene, where expression of a protein known as Podocin occurs. Abnormal or inefficient signaling through Podocin protein-dependent networks contributes to the development of podocyte dysfunction and proteinuria. The human NPHS2 gene maps to chromosome 1q25-q31 and encodes a 383 amino acid protein. Podocin is an integral membrane protein that appears to fold into a hairpin-like structure with intracellular amino- and carboxy-termini. Transmembrane and cytoplasmic portions of Podocin share homology to the corresponding regions of the stomatin family proteins. Expression of high-order oligomers of Podocin in glomerular podocytes may reflec |
|---|
| Immunogen | n/a |
|---|
| Other Names | nephrosis 2 idiopathic steroid-resistant, PDCN, SRN1, podocin |
|---|
| Gene, Accession # | Entrez: 7827; Uniprot: Q9NP85 |
|---|
| Catalog # | PA5-61987 |
|---|
| Price | |
|---|
| Order / More Info | Podocin Antibody from INVITROGEN ANTIBODIES |
|---|
| Product Specific References | n/a |
|---|