| 产品详情 |
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| Antigenic Specificity | SRSF2 |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human |
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| Isotype | n/a |
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| Format | purified |
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| Size | 100 µl |
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| Concentration | n/a |
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| Applications | Immunocytochemistry: 1-4 µg/mL, Immunofluorescence: 1-4 µg/mL, Immunohistochemistry: 1:200-1:500, Western Blot: 0.4 µg/ml |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | SRSF2 Polyclonal Antibody. SFRS2 is necessary for the splicing of pre-mRNA. The protein is required for formation of the earliest ATP-dependent splicing complex and interacts with spliceosomal components bound to both the 5'- and 3'-splice sites during spliceosome assembly. It also is required for ATP-dependent interactions of both U1 and U2 snRNPs with pre-mRNA. And it interacts with other spliceosomal components, via the RS domains, to form a bridge between the 5'- and 3'-splice site binding components, U1 snRNP and U2AF. It binds to purine-rich RNA sequences, either 5'-AGSAGAGTA-3' (S=C or G) or 5'-GTTCGAGTA-3' and can bind to beta-globin mRNA and commit it to the splicing pathway. |
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| Immunogen | n/a |
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| Other Names | SC-35 , SFRS2 |
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| Gene, Accession # | Entrez: 6427; Uniprot: Q01130 |
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| Catalog # | PA5-62086 |
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| Price | |
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| Order / More Info | SRSF2 Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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