| 产品详情 |
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| Antigenic Specificity | RIP1 |
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| Clone | oligoclonal |
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| Host Species | Recombinant Rabbit |
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| Reactive Species | human |
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| Isotype | IgG |
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| Format | purified |
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| Size | 100 µg |
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| Concentration | n/a |
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| Applications | Immunocytochemistry: 5 µg/mL, Immunofluorescence: 5 µg/mL, Western Blot: 2.5 µg/mL |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | RIP1 Antibody, ABfinity™ Rabbit Oligoclonal. RIP1 (Receptor Interacting Protein), also known as RIPK1, is a crucial 74 kDa adaptor kinase in several of stress-induced signaling pathways. RIP1 contains an N-terminal region with homology to protein kinases, an intermediate domain capable of association with MAPKKK and a C-terminal region containing a death domain motif present in the Fas and TNFR1 intracellular domains. Full length RIP1 is important for signaling to NF-kappa-B, MAPKs and necrosis, whereas caspase-8 generates a C-terminal RIP1 cleavage fragment, promoting TNF-induced apoptosis. It is required for TNFRSF1A-mediated and TLR3-induced NF-kappa-B activation. RIP1-deficient mice fail to thrive, displaying extensive apoptosis i |
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| Immunogen | n/a |
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| Other Names | RIP, RIP1 |
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| Gene, Accession # | Entrez: 8737; Uniprot: Q13546 |
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| Catalog # | 711689 |
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| Price | |
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| Order / More Info | RIP1 Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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