| 产品详情 |
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| Antigenic Specificity | RIP1 |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human |
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| Isotype | n/a |
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| Format | purified |
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| Size | 100 µL |
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| Concentration | n/a |
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| Applications | Immunocytochemistry: 1:100-1:1000, Immunofluorescence: 1:100-1:1000, Western Blot: 1:1000-1:10,000 |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | RIP1 Polyclonal Antibody. Essential adapter molecule for the activation of NF-kappa-B. Following different upstream signals (binding of inflammatory cytokines, stimulation of pathogen recognition receptors, or DNA damage), particular RIPK1-containing complexes are formed, initiating a limited number of cellular responses. Upon TNFA stimulation RIPK1 is recruited to a TRADD-TRAF complex initiated by TNFR1 trimerization. There, it is ubiquitinated via 'Lys-63'-link chains, inducing its association with the IKK complex, and its activation through NEMO binding of polyubiquitin chains. |
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| Immunogen | n/a |
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| Other Names | RIP, RIP1, RIP-1, cell death protein RIP, receptor interacting protein, receptor-interacting protein 1, receptor-interacting serine/threonine-protein kinase 1, serine/threonine-protein kinase RIP |
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| Gene, Accession # | Entrez: 8737; Uniprot: Q13546 |
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| Catalog # | PA5-29223 |
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| Price | |
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| Order / More Info | RIP1 Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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