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Product Name | GSK-269962 hydrochloride |
Description | MW: 607.07. Purity ≥98% by HPLC. GSK-269962 is a potent and selective Rho kinase (ROCK) inhibitor (IC50 values are 1.6 and 4 nM for recombinant human ROCK1 and ROCK2 respectively). It displays >30-fold selectivity for ROCK against a panel of serine/threonine kinases. Induces vasorelaxation in preconstricted rat aorta (IC50 = 35 nM) and lowers blood pressure in a rat model of hypertension. |
Size | 5 mg |
Concentration | n/a |
Applications | n/a |
Other Names | GSK26996B, GSK-269962A, N-[3-[[2-(4-amino-1,2,5-oxadiazol-3-yl)-1-ethyl-1H-imidazo[4,5-c]pyridin-6-yl]oxy]phenyl]-4-[2-(4-morpholinyl)ethoxy]-benzamide hydrochloride, GSK269962 |
Gene, Accession, CAS # | CAS: 2095432-71-4 |
Catalog # | B2425-5 |
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Order / More Info | GSK-269962 hydrochloride from BIOVISION, INC. |
Product Specific References | n/a |
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