| 产品详情 |
| Edit |   |
| Antigenic Specificity | UAP1L1 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human |
| Isotype | n/a |
| Format | purified |
| Size | 100 µl |
| Concentration | n/a |
| Applications | Immunocytochemistry: 1-4 µg/mL, Immunofluorescence: 1-4 µg/mL, Immunohistochemistry: 1:200-1:500, Western Blot: 0.4 µg/mL |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | UAP1L1 Polyclonal Antibody. UAP1 is a 56KDa isoform which catalyzes the final step of UDP-N-acetylglucosamine (UDP-GlcNAc) biosynthesis from fructose-6-phosphate. UDP-GlcNAc, the activated form of GlcNAc moiety is used as a key precursor in N-linked glycosylation and the glycosylphosphatidylinositol (GPI)-anchor of cellular proteins. Crystallization studies revealed UAP1 is composed of a large central core flanked by two smaller extra domains. The central main domain displays a / structure resembling the Rossmann fold. Northern Blot analysis detected abundant expression of UAP1 in testis and sperm with a low expression in placenta, muscle and liver. It is implicated in antibody-mediated infertility in males. |
| Immunogen | n/a |
| Other Names | UAP1 |
| Gene, Accession # | Entrez: 91373; Uniprot: Q3KQV9 |
| Catalog # | PA5-60688 |
| Price | |
| Order / More Info | UAP1L1 Antibody from INVITROGEN ANTIBODIES |
| Product Specific References | n/a |
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